As Novo Nordisk boosts Wegovy, Ozempic AD spend, analysis finds a rising tide lifts all boats for diabetes, weight-loss drugs
When you lose weight, your metabolism adjusts downward to conserve energy, and hunger-regulating hormones like ghrelin rebound to defend your new (lower) weight
It makes your stomach muscle contractions weaker and slower than they need to be to digest your food and pass it on to your intestines
Eastwood PR, Barnes M, MacKay SG, et al
doi: 10.1111/bph.13384 15 UsdinTBMezeyEButtonDCBrownsteinMJBonnerTI
Additional considerations include: Dietary quality changes during weight loss programmes Increased urinary magnesium excretion in poorly controlled diabetes (though GLP-1 therapy typically improves glycaemic control) Concurrent medications that may affect magnesium status, such as proton pump inhibitors or diuretics It is important to note that routine magnesium monitoring is not currently recommended in NICE guidance (NG28) for patients on GLP-1 therapy
